Download E-books Side Reactions in Organic Synthesis: A Guide to Successful Synthesis Design PDF

By Florencio Zaragoza Dörwald

Such a lot syntheses within the chemical study laboratory fail and customarily require a number of makes an attempt ahead of continuing satisfactorily. Failed syntheses aren't purely discouraging and difficult, but additionally fee loads of time and cash. Many mess ups may perhaps, notwithstanding, be shunned by way of figuring out the structure-reactivity courting of natural compounds.
This textbook highlights the competing procedures and obstacles of an important reactions utilized in natural synthesis. by means of permitting chemists to quick realize strength difficulties this booklet can assist to enhance their potency and success-rate. A needs to for each graduate scholar but in addition for each chemist in and academia.
Contents:
1 natural Synthesis: normal Remarks
2 Stereoelectronic results and Reactivity
three the steadiness of natural Compounds
four Aliphatic Nucleophilic Substitutions: troublesome Electrophiles
five The Alkylation of Carbanions
6 The Alkylation of Heteroatoms
7 The Acylation of Heteroatoms
eight Palladium-Catalyzed C-C Bond Formation
nine Cyclizations
10 Monofunctionalization of Symmetric Difunctional Substrates

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